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Resolution LC/MS-MS

Discussions about GC-MS, LC-MS, LC-FTIR, and other "coupled" analytical techniques.

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Resolution LC/MS-MS

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pharm2004
Hi,
I have to separate two peaks at LC Side for LC/Ms-Ms analysis. Can I quantify overlapping two peaks?

Thanks

Re: Resolution LC/MS-MS

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James_Ball
Hi,
I have to separate two peaks at LC Side for LC/Ms-Ms analysis. Can I quantify overlapping two peaks?

Thanks
If the two peaks have unique parent:daughter transition masses then if they co-elute you can still quantify them. If they are isomers with the same transition masses then you need to separate.
The past is there to guide us into the future, not to dwell in.
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