limit of water content in sample for GC-MS analysis

[s2008]

hello All,

There are some columns that can tolerate direct injection of aqueous sample and related papers were frequently published. however, Most of this kind of method was using GC-FID. i.e FID as an sole detector. I just wonder whether GC-MS can be used to direct injection of aqueous sample? If not, do you have any idea about the limit of water content in sample for Gc-Ms analysis?


Thanks advance

[jh1]

hello All,

There are some columns that can tolerate direct injection of aqueous sample and related papers were frequently published. however, Most of this kind of method was using GC-FID. i.e FID as an sole detector. I just wonder whether GC-MS can be used to direct injection of aqueous sample? If not, do you have any idea about the limit of water content in sample for Gc-Ms analysis?


Thanks advance

No, Water ionizes in the source very easily and has a nasty habit of reacting with pretty much anything else in your sample. Keeping total water content under 1% is a good idea.

[AICMM]

s2008,

Water also takes a long time to pump out of the vacuum system which is why a pumpdown is often more about getting water under control than it is about getting rid of all the air.

Yech.

Best regards.