-
- Posts: 4
- Joined: Tue Jun 10, 2008 2:53 pm
Advertisement
FLow rate problem
Discussions about HPLC, CE, TLC, SFC, and other "liquid phase" separation techniques.
3 posts
Page 1 of 1
My HLPC won;t seem to work at higher flow rates, It will not even purge/prime the lines as the flow rate is to high, it'll get to a point in pressure and shut off, when it is set to except these pressures. Any ideas?
-
- Posts: 397
- Joined: Fri Sep 22, 2006 7:36 am
Please detail your question!
What brand of HPLC system are you using? Is column installed? At which pressures you have observed pump shut down, etc
What brand of HPLC system are you using? Is column installed? At which pressures you have observed pump shut down, etc
-
- Posts: 835
- Joined: Thu Apr 14, 2005 7:00 am
on some pumps there is a frit that when blocked produces a lot of pressure with a column or at high flow rates when purging/primimg.
it could be that a certain part of the tubing is blocked also.
or simply maybe the settings of maximum pressure for your pump are too low and it shuts itself because of that.
what is your pump brand?
it could be that a certain part of the tubing is blocked also.
or simply maybe the settings of maximum pressure for your pump are too low and it shuts itself because of that.
what is your pump brand?
3 posts
Page 1 of 1
Who is online
In total there are 26 users online :: 4 registered, 0 hidden and 22 guests (based on users active over the past 5 minutes)
Most users ever online was 4374 on Fri Oct 03, 2025 12:41 am
Users browsing this forum: Ahrefs [Bot], Google [Bot], Majestic-12 [Bot], Semrush [Bot] and 22 guests
Most users ever online was 4374 on Fri Oct 03, 2025 12:41 am
Users browsing this forum: Ahrefs [Bot], Google [Bot], Majestic-12 [Bot], Semrush [Bot] and 22 guests
Latest Blog Posts from Separation Science
Separation Science offers free learning from the experts covering methods, applications, webinars, eSeminars, videos, tutorials for users of liquid chromatography, gas chromatography, mass spectrometry, sample preparation and related analytical techniques.
Subscribe to our eNewsletter with daily, weekly or monthly updates: Food & Beverage, Environmental, (Bio)Pharmaceutical, Bioclinical, Liquid Chromatography, Gas Chromatography and Mass Spectrometry.
- Follow us on Twitter: @Sep_Science
- Follow us on Linkedin: Separation Science
