pre column filter or guard column

[asaramito]

I would like to know if I can use a precolumn filter whithout a guard column?

thank you

[tom jupille]

yes

[Uwe Neue]

Yes you can, but a precolumn filter gives you less protection than a guard column. If indeed the problem is only particulate debris, then both work equally well. If the problem is something else, guard columns provide a better protection.

[cactus]

I've heard so much about guard column, in what circumstances do we use a guard column? And what is a guard column?

[JGK]

I've heard so much about guard column, in what circumstances do we use a guard column? And what is a guard column?

http://www.restek.com/aoi_general_A015.asp

Especially useful if the sample matrix is not particularly "clean".