Hi everyone
Ineed to ask anyone have an experience in alendronate as abioequivalent study
I want to ask is it easy to handle it
Ihave an API4000 mass spectrometrey (triple quad).

which is better to analyze from urine or plasma
is it necessary to do derivitization for samples or no need if it analyzed on mass spectrometry

I didnt start development yet but i want take an idea about its problems!!