splitter advice

[mariojon]

Hello,

Well here is the problem I am using LCMS with ESI probe . The Mass system is waters ZQ4000 and what I want to ask is what type of splitter is best . eg low pressure , high pressure splitter valves. where i need only 0.2ml to flow to the mass . Will PEEK material or steel be better.
Also please suggest me good post column switching valve( Company).

Thank you
John

[bert]

Hi John,

Why dont you use columns with smaller ID's, so you can work with lower flows?

[vicou_chen]

Hello,

Well here is the problem I am using LCMS with ESI probe . The Mass system is waters ZQ4000 and what I want to ask is what type of splitter is best . eg low pressure , high pressure splitter valves. where i need only 0.2ml to flow to the mass . Will PEEK material or steel be better.
Also please suggest me good post column switching valve( Company).

Thank you
John

in my opinion,you should use a PEEK material splitter.because PEEK material can preferably resist your solvent and sample properties.

[H.Thomas]

I have experimented with different setups for flow splitters for our Shimadzu LCMS 2010. I was nor very successful with homebrew solutions (i.e. a tee with different lengths of PEEK capillaries). The reason is, that the backpressure of the ESI changes, and so the split ratio was not constant over more than a few runs.

Finally I bought an ASI Quick-Split variable flow splitter (http://www.hplc-asi.com/pdf/FSPB2003np.pdf) that was very expensive but worked satisfactorily so far.

Regards, Hartmut