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hplc method for lamivudine, zidovudine and nevirapine
Posted: Sun Jul 01, 2007 3:07 pm
by bedse.gaurav
can anybody tell me a method which will simultaneously determine lamivudine, zidovudine and nevirapine.
and which will be the prefered pH.
Posted: Sun Jul 01, 2007 4:59 pm
by Uwe Neue
I suggest a silica HILIC column (Atlantis HILIC). Start off with a gradient from 90% acetonitrile to 50% acetonitrile. Then narrow the gradient and/or adjust the pH.
HIV drug
Posted: Mon Jul 02, 2007 2:59 am
by Kasiban
I used ammonnium acetate and MeOH in gradient.
flow rate 0.4 ml/min in UPLC.
column : Acquity BEH C18, 2.1x50mm,1.7um.
and analysis time was 4 min.
e-mail to me, I will give you more information
kasiban@hotmail.com
LZN
Posted: Thu Jul 05, 2007 11:19 am
by msrinureddi
I have the method, why do you require this? regds/MSReddy
Re: LZN
Posted: Mon Jul 16, 2007 2:19 pm
by bedse.gaurav
I have the method, why do you require this? regds/MSReddy
i am working on these grugs. i got project.