if any body have a good HPLC method for cefdinir?

[dhru]

[danko]

Dear dhru,

You could at least use a couple of seconds to finish the sentence, in return for all this time you expect the folks on this forum to invest in finding an analytical procedure as required

[dhru]

Dear Danko

i all ready tried on different pH but i am unable to get a good peak shape of cefdinir.i know that pH is not only the criteria to get good peak shape.
i check it by changing different column , organic solvents,diluent ,organic modifier , eventhough i didnt get good peak shape

[Noser222]

People will be more willing to help you if you post all of the conditions of your method.
List the column, mobile phase, and sample concentrations and diluent.

[Bruce Hamilton]

Method development for the determination of cefdinir and its related substances by high-performance liquid chromatography.
Okamoto Y, Itoh K, Namiki Y, Matsushita J, Fujioka M, Yasuda T.
J Pharm Biomed Anal. 1996 Apr;14(6):739-48.

Isolation, structural elucidation and characterization of impurities in Cefdinir.Rao KV, Rani A, Reddy AV, Bharathi CH, Dandala R, Naidu A.
J Pharm Biomed Anal. 2006 Dec 14

Bruce Hamilton

[dhru]

Thank you very much
i got that method but still i have one question that can we use dioxane in our mp. they gave 20 ml in 800 ml
dhru