Why CCV failed?

[John2006]

Hello everyone,

I'm new to GC so there are so much things that I don't know about.

Question: Why do we need the CCV, LCS/LCSD/, MS/MSD, and surrogate? and why my CCV keep failing most of the time even though i do everything exactly the same, please give me come common circumstances?

This question is kind of vague, but hopefully someone can answer my question.

Thanks.

[Mary Carson]

Not everyone uses the same abbreviations (with exception of GC...). You might get a bet response to your question if you spell out your acronyms.

[L4br4t]

I assume the acronyms are as follows:

CCV = continuing calibration verification
LCS = low concentration standard ( or spike)
LCSD = LCS duplicate
MS = matrix spike
MSD = MS duplicate

Yes your question is kind of vague, and in fact very broad.
It seems that it is more about methodology rather than chromatography alone.
I suggest you do some research to learn about quality control / quality assurance and why it is so important. There is just too much information to post in one reply.
As for the failing CCV issue, we could use a little more information in order to determine your problem.