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CHIRAL HPLC COLUMN

http://www.chromforum.org/viewtopic.php?t=4113

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CHIRAL HPLC COLUMN

Posted: Wed Jun 07, 2006 2:11 pm
by Harry
Hi,

I am new to chiral chromatography. Can anyone suggest method for seperation of isomers of salbutamol / ramipril. I am using AGP column from JT baker. A couple of pirkle type columns are lying with me. Will the same application will work on DNBPG((R)-N-3,5-Dinitrobenzoylphenyl glycine) column or DNB-LEU(S)-N-3,5 Dinitrobenzoyl leucine column. If anybody have method for same, please send to me. This will same hell lot of my time and cost.

Posted: Wed Jun 07, 2006 6:36 pm
by Bruce Hamilton
Why not ask the manufacturers of your columns?. Most chiral manufacturers offer free technical support.

If your AGP column is similar to ChromTech's ( which complies with USP L41 ), their www site has an application example for salbutamol.

Bruce Hamilton
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