Procedure for glass silanization

[dcav]

Hi everybody!

I have a question which isn't probably strictly chromatographyc, but i'm sure that someone could help me.

I know that with packed columns in GLC when were used silica support, they were modified in the surface by silanization reaction to avoid strong interactions with analites.

I need to modifie in the same way a glass film (more or less like the ones for microscope) can someone suggest me the reagents and reaction conditions?

Thank you very much

[mbulentcakar]

Hi,
You will need to keep it in a (roughly) 5% solution of dimethyldichlorosilane in toluene for about 30 minutes. Then you may rinse and dry.
Good luck

[Flop]

For a detailed description ( including safety ) see:

http://www.fluorochemsilanes.co.uk/glas ... vation.htm

best of luck

Flop