Donepezil

[christos]

Hi to everyone and good morning from sunny Athens,
i am trying to collect some information about donepezil hydrocloride. I found a lot but i cannot find information on solubility of that compound.
Does anybody knows about solubility of donepezil hydrochloride in organic solvents??? (I mean the accurate percentages)
Thanx in advanced

PS: I have found solubility numbers of donepezil but not for the hydrochoric salt.

[aniket]

you can go to pfizer website search for the monograph of Aricept (Donepezilm HCL) also it is listed in Merck Index 14th Edtn, plesae check chemcial abtsarcs also, there are lots of resouresces you have to find needle in the haystack

ok

have good time in sunny athens, it is super sunny here in mumbai, with 92 % humidity, so literally we are sweating t out

[christos]

thanx a lot for your help,
i have been in Pfizer website and there is some information but not accurate numbers. As for Merck index i am not registered there. Anyway, i will look in chemabstracts, i just wondering if someone has any more 'fast' information, as in order to do a properly search i should spend some hours outside from my workplace.
again thanx for your answer

[aniket]

i think you have spend some hours in the library to get this, or else u can practically do an spectrophotometric assay of donepzil to find out solubility, why do you have to registerd for merck index, you can find it in printed merck index, sometimes it is good to go back to old times ok

sorry for bothering you

From Super Hot Mumbai

[syx]

Merck Index 14th?
I think it will available September 2006...