Can I use splitless liner for split injection?

[zimanli]

Is it true that splitless injection would make my injection port dirty faster than split injection? How many injections shall I change liner and spetum?

Thanks a lot!

[KC]

all depends on what you are shooting and your method parameters. If you are saying you typically run split and are worried about running splitless, no. Under the right conditions I have run literally hundreds of injections with no problem whatsoever, all splitless. Can't remember the last method where I ran split. Make sure you have in your method to open vent after about 30 sec to 1 min. alot depends on your compound and the concentration you are shooting.

[KC]

As far as how often to change liner and septum, not until your chromatography tells you to.
Whats the saying, never trouble troubles, till troubles trouble you.