Vespel vs isopropanol

[Cotton Hawes]

Hello everybody.

I faced a trouble with my HPLC - exceeding pressure in injection flow path. I diassembled the injection valve and washed the rotor seal (vespel) in water then isopropanol using ultrasonic bath.
Then i assembled the valve, it worked well for several injection, but now it leaks severely. Could the isopropanol somehow damage the vespel rotor seal?

[Gerhard Kratz]

Vespel and Isopropanol should be no problem. Please check for scratches on the rotor seal and the rotor seal housing.