Advertisement

Switching two columns

Discussions about HPLC, CE, TLC, SFC, and other "liquid phase" separation techniques.

2 posts Page 1 of 1
Hello,

I am facing one problem, we have two analysis with two different columns, also we have two different movil fases. When we change from one column to the other, it takes aproximately 3 hours to accondition the column for the analysis. So we are thinking in a switching system but to make it automatic we need to have a more complicated system and to a simple one as we understand. I have make a presentation where you can see this problem. You can see it in the following address:
https://www.dropbox.com/s/8q253sdjdiu3w ... es%20A.pdf

Has someone had a similar problem and how have resolved it?

Thank you for your answers.

Regards,

Adolfo Alvarez
Life is a game, and in a game you can win or loose, but it is still a game.
Without knowing what the mobile phases are (and their degree of compatibility) it's hard to tell.
-- Tom Jupille
LC Resources / Separation Science Associates
tjupille@lcresources.com
+ 1 (925) 297-5374
2 posts Page 1 of 1

Who is online

In total there is 1 user online :: 0 registered, 0 hidden and 1 guest (based on users active over the past 5 minutes)
Most users ever online was 4374 on Fri Oct 03, 2025 12:41 am

Users browsing this forum: No registered users and 1 guest

Latest Blog Posts from Separation Science

Separation Science offers free learning from the experts covering methods, applications, webinars, eSeminars, videos, tutorials for users of liquid chromatography, gas chromatography, mass spectrometry, sample preparation and related analytical techniques.

Subscribe to our eNewsletter with daily, weekly or monthly updates: Food & Beverage, Environmental, (Bio)Pharmaceutical, Bioclinical, Liquid Chromatography, Gas Chromatography and Mass Spectrometry.

Liquid Chromatography

Gas Chromatography

Mass Spectrometry