Chromatography Forum

Posted: **Mon Aug 15, 2005 6:13 am**

Dear All,

Could any one help me in listing of parameters to be done for uncertainity measurements for chromatograpghy like GC, GC-MS and LC-MS/MS.
Even relevant literaturs also will do.

Thanking you in advance.

With best regards

N.Bhuvaneswaran

Posted: **Tue Aug 16, 2005 6:29 am**

Uncertainity of chromatography is associated with method of analysis.

It can be evaluated from the method validation parameteres like Secificity, Precision, Accuracy & range.

More comments please.

Regards,
Hemal

Posted: **Tue Aug 16, 2005 11:27 pm**

You can refer the following link

http://www.fda.gov/ora/science_ref/lm/v ... _04_06.pdf

Posted: **Fri Aug 26, 2005 10:43 am**

EURACHEM/CITAC Guide
Quantifying Uncertainity in Analytical Measurement
Example 4 (phosphorous pesticide by GC)

You can download id from EURACHEM site

Posted: **Fri Sep 02, 2005 12:14 pm**

for cal curves, there are formulas for calculating the uncertainty in the concentration based on the uncertainty in the slope and intercept.

Chromatography Forum

Uncertainity measurements in chromatography

Uncertainity measurements in chromatography

Uncertainity

least squares