Detector noise
Posted: Tue Oct 16, 2012 9:18 am
by StephenO
On Waters 2489,2487 2996 and 2998 detectors how should I test for detector noise and also how often should this be preformed.
Is this a required by the FDA?
Thanks
Re: Detector noise
Posted: Tue Oct 16, 2012 6:07 pm
by tom jupille
This should be a standard part of your performance qualification (PQ). Yes, it is required, but how often is a matter of your company's SOPs. I would say annually as a minimum and any time the detector has been worked on.
If you use Empower, you can check it:
http://www.waters.com/webassets/cms/sup ... ower_2.pdf
There is also an ASTM practice: E1657-98
Re: Detector noise
Posted: Fri Oct 19, 2012 2:27 pm
by StephenO
Thanks for your help Tom