Analysis of Polydimethylsiloxane

[carol]

Dear all,

I would like to analyze polydimethylsiloxane and I think I can use HPLc-MS/MS but I cannot find application notes for it . Have anybody analyzed this compound? I will really appreciate any comment or suggestion.

Thanks in Advance,

Carolina

[rhaefe]

Since PDMS are polymers size exclusion chromatography is most commonly used (toluene, chloroform or THF as mobile phase). To analyze any residual cyclics or other low molecular compounds GC-FID (or GC-MS) is the method of choice.
A nice little summary of various analytical techniques for PDMS can be found here:
http://www.dowcorning.com/content/publi ... apter2.pdf

Wyatt has one application note on their web site (application note #39):
http://wyatt.com/literature/application ... ymers.html

[carol]

Great!!!

Thanks a lot!!

Carol

[Kristof]

Has anyone know of a method for quantification of PDMS using LC-MS?

[fverdi163]

Since PDMS are polymers size exclusion chromatography is most commonly used (toluene, chloroform or THF as mobile phase). To analyze any residual cyclics or other low molecular compounds GC-FID (or GC-MS) is the method of choice.
A nice little summary of various analytical techniques for PDMS can be found here:
http://www.dowcorning.com/content/publi ... apter2.pdf

Wyatt has one application note on their web site (application note #39):
http://wyatt.com/literature/application ... ymers.html

Links broken. Anyone could share new infos ? I need to analysis PDMS too on HPLC MS. Anyone know their Precursor Ionz ? I have a c18 column. ACN/phosphoric acid 0,1 m.mol phase.