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Internal Standard for solketal

Posted: Sat Jan 07, 2012 6:44 pm
by malaya
Hey Guys
I was wondering for an internal standard for quantification of solketal in my product.
If any idea , Please let me know.
Thanks,

Re: Internal Standard for solketal

Posted: Sun Jan 08, 2012 9:07 pm
by Don_Hilton
My favorite place to find an internal standard is the chemicals shelf in the lab. Look for something of similar molecuar weight and polarity. Perhaps something with a tetrahydrofuran ring in it and an alcohol functionallity... The ideal internal standard would be an isotopically labeled analog to what you are analyzing - as long as the compound will not react with anything in the sample or in analysis steps.

Re: Internal Standard for solketal

Posted: Fri Jan 27, 2012 12:24 am
by malaya
My favorite place to find an internal standard is the chemicals shelf in the lab. Look for something of similar molecuar weight and polarity. Perhaps something with a tetrahydrofuran ring in it and an alcohol functionallity... The ideal internal standard would be an isotopically labeled analog to what you are analyzing - as long as the compound will not react with anything in the sample or in analysis steps.

Thank you very much. I got it.