Headspace parameters question

[Mike H.]

I was hoping someone could give me an idea about what to consider when deciding on what to set loop fill time,loop equilibration time and injection time when using a Agilent G1888 HS with a HP6890 GC. I would also appreciate links to good online resources to learn about theory and method development of HS GC methods. I also understand this is a business so links to online pay classes are good too. ty

[chromatographer1]

There are good books written by authors associated with Perkin Elmer, the pioneer in headspace analysis.

Headspace is mostly common sense, and a good intuition can be gained by a little experimentation. Read a little about Henry's law and spend a little time experimenting and you will be on your way to comprehending the technique.

Best wishes,

Rod

[krickos]

Hi

One favourite of mine is "Static headspace-gasChromatography" theory and practise by Bruno Kolb and Leslie S. Ettre.

General recommendations/intervals for the parameters you mentioned should be included in your manual from Agilent.

[Bigbear]

You can search Agilent.com for app notes.