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Huge solvent peak with good baseline
Posted: Sat Oct 22, 2011 9:32 pm
by Rmahat
What is the most contributing cause amongst following in the huge solvent peak?
1. Leaking injector
2. High split ratio
3. Very low sample concentration
4. low temperature at injector
5. Dirty liner
Re: Huge solvent peak with good baseline
Posted: Sat Oct 22, 2011 10:29 pm
by chromatographer1
4.
If you mean too large of an injection for #3, then 3 is correct as well, otherwise, just #4.
If #5 was a VERY dirty injection port, lots of junk coating everything, then yes to #5 as well.
Most common cause is a blocked splitter or splitter valve not open at inject time.
best wishes,
Rod
Re: Huge solvent peak with good baseline
Posted: Mon Oct 24, 2011 5:10 pm
by CE Instruments
It can also be a very low flow rate due to either blockage or operator error.
Re: Huge solvent peak with good baseline
Posted: Wed Oct 26, 2011 1:53 pm
by Bigbear
Don't forget liner "overloading".
You could aso try opening the split vent sooner.
Re: Huge solvent peak with good baseline
Posted: Sun Oct 30, 2011 12:50 am
by Rmahat
I fixed it. I was using low solvent void time. I increased it and it got fixed. Thank you very much for all your efforts.