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- Posts: 42
- Joined: Wed Sep 14, 2011 1:47 pm
1. I analyze Metformin with HPLC and recieved a long - tailng peak, therefore I added a little Trimethylamine to my buffer to shorten my peak's tailing. It appears to work, my peak becames better. But I wonder if there are some problems happen beside this good side?
2. Can elements of mobile phase (pH, composition ...) increase or decrese peak's area?