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Liquinox in LC
Posted: Tue Sep 06, 2011 2:00 am
by diliplakkad
Liquinox is a detergent which use to clean pharmaceutical manufacturing machines. while product change over, cleaning verification must be passed. Which LC column and what chromatographic condition should be used to detect Liquinox peaks?
Re: Liquinox in LC
Posted: Tue Sep 06, 2011 12:45 pm
by DR
If Google has nothing, check with the manufacturer of Liquinox.
Re: Liquinox in LC
Posted: Wed Sep 07, 2011 1:14 pm
by bhuvfe
Find out which class of surfactant is and maybe try this column
http://www.dionex.com/en-us/webdocs/417 ... -Jul09.pdf
Good luck!
Re: Liquinox in LC
Posted: Wed Sep 07, 2011 11:12 pm
by rhartwick
Why not use a non-selective technique like TOC to determine residue? If not, you should be able to develop an HPLC separation at low wavelength (200 nm or so) fairly quickly. Just start with a C18 column and water/acetonitrile and get a basic separation, then go from there.