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purity of impurity reference standard

Discussions about HPLC, CE, TLC, SFC, and other "liquid phase" separation techniques.

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Hi, if a material was approximately 60 % pure, could it be used for an impurity reference standard, given that a standard, by definition, has to be pure.

Thx

Tina

If that's the best you can do, the answer is a qualified "yes". The qualifications:
- do you have a way of finding out exactly how pure it is? If yes, then you can correct the response accordingly
- are the "impurities in the impurities" likely to interfere with anything else?
- What kind of precision do you require for the measurement of that impurity? At the trace level, 15-25% may be acceptable, in which case you may only need to know your standard to a few percent.
-- Tom Jupille
LC Resources / Separation Science Associates
tjupille@lcresources.com
+ 1 (925) 297-5374
2 posts Page 1 of 1

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