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HPLC with ELSD Detector

http://www.chromforum.org/viewtopic.php?t=13704

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HPLC with ELSD Detector

Posted: Wed Aug 25, 2010 2:51 pm
by aprilcparker
Hello,

I am trying to develop a method for a surfactant using HPLC with an ELSD detector. I am trying to figure what initial parameters need to be set such as the signal, the gain in order to optimize my method. I currently have the gain set to 12 and the signal at 1, but I am not getting any peaks. Any help would be greatly appreciated. Thanks in advance :D !

Posted: Wed Aug 25, 2010 7:02 pm
by tom jupille
Depends on the manufacturer and model. I would contact the manufacturer or check their web site for applications notes to give you an idea of "typical" settings.
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