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HPLC analysis of menthol

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HPLC analysis of menthol

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GT
Hi,
is it possible to analyze menthol by HPLC without any derivatizzation? Is it also possible to separate the two isomers l-menthol and d-menthol?
Any suggest will be appreciate.
Thanks in advance.

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Consumer Products Guy
We've only used GC here for menthol assay.

Most organic species can be detected by HPLC at low UV if the matrix contains no interfering species, and often times using refractive index detector.

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JGK
Found a reference to a normal phase method here http://www.informaworld.com/smpp/conten ... 651&db=all
Good judgment comes from bad experience, and a lot of that comes from bad judgment.
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