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Monolithic column

Discussions about HPLC, CE, TLC, SFC, and other "liquid phase" separation techniques.

7 posts Page 1 of 1
Hi all,

I've read about a kind of particles in LC called monolithic. Could any one explain what it is and the advantages of that kind of columns.

Thanks.

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Dancho Dikov
Main different is in their internal structure. While packed columns are filled with spherical particles, monolithic column is filled with one piece of porous material - monolith.

There are two kinds of monoliths: inorganic silica based (Merck) and organic polymers monoliths (different types of monomers and crosslinker - methacrylates, styrene-divinylbenzene, acrylates, ..).

Main advantages of the organic polymers monoliths is their simple preparation and very easy and extensive surface modification (reactive monomers, chemical modification, grafting). On the other hand, majority of them is still developed in the research labs.

If you like I can provide you with more literature, depends on your requirements.
HPLC 2017 in Prague, http://hplc2017-prague.org/

Thank you both.

Yes I d like to have some more literature. If possible, please send me

Regards

my email: thohry@yahoo.com

If possible, please send me
done
HPLC 2017 in Prague, http://hplc2017-prague.org/

plz send me toooo
my mail is nageshiict@gmail.com

done
HPLC 2017 in Prague, http://hplc2017-prague.org/
7 posts Page 1 of 1

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