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ELS Detector sensitivity query

http://www.chromforum.org/viewtopic.php?t=12143

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ELS Detector sensitivity query

Posted: Thu Jan 28, 2010 12:25 pm
by wrighty
Hello All,

I am running an application with a SEDEX75 Evaporative Light Scattering Detector and have a query regarding sensitivity.

I am trying to increase the sensitivity of the system by adjusting the GAIN but i have little knowledge of what the gain is/does. Would i need to increase or decrease the gain? any explanation would be usefull

Many Thanks

Steve

Posted: Thu Jan 28, 2010 5:22 pm
by Kostas Petritis
You need to increase it, and for Sedex 75 the optimum is generally between 8 and 10 (but it will depend on the background of your mobile phase).

Posted: Thu Feb 04, 2010 11:00 pm
by netsking88
Increase temperature a little bit will increase sensitive too.
of course your sample should be non-vol.
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