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dialkyl fosfates or OP with CG-ECD or HPLC-UV?

Posted: Fri Jan 15, 2010 1:04 pm
by Juan Pedro
Hi!!

Does anyone have a method for measuring dialkyl fosfates or OP pesticides in biological samples with CG-ECD or HPLC-UV?

Thank you very much

Posted: Fri Jan 15, 2010 1:16 pm
by fsistere
Hi
To analize OP pesticides in GC, i think the ECD is not the correct detector. You can use a NPD or a MS.

Posted: Fri Jan 15, 2010 1:45 pm
by Juan Pedro
I thought the same but I checked one paper in which they analyse DAP in air using CG-ECD.

Environmental and biological monitoring of exposure to organophosphorus pesticides: Application to occupationally and non-occupationally exposed adult populationsJournal of Exposure Science and Environmental Epidemiology (2006) 16, 417–426.

That´s why I thought it would be possible

Posted: Sun Jan 17, 2010 5:02 pm
by AICMM
Juan Pedro,

I looked at generic structure of DAP's and would not see how they would be great responders on ECD but I have not actually tried it so...

Have you considered derivatization with PFBB prior to ECD analysis? Otherwise, I should think NPD would be a better detector.

Best regards.