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Impurity Standard Issue

http://www.chromforum.org/viewtopic.php?t=118314

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Impurity Standard Issue

Posted: Fri Aug 19, 2022 12:28 pm
by Mouleyre
I am trying to validate an already existing rel subs method for a new impurity. It is available commercially but leads to 3 peaks upon injection on HPLC-UV. I notice all the CoAs for the standard online the purity is assessed by GC.

What would be the reason in this instance why GC would work better?

Re: Impurity Standard Issue

Posted: Sat Aug 20, 2022 8:29 am
by vmu
Name the impurity please. Is it a secret compound?
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