CAM Column for Glycerol

[TimGG]

Does anyone know is it possible to use GC-FID CAM column to detect glycerol??

If it is possible, can you tell me what's the setting on the GC?? I'm using Aglient 7890A, thanks for your help!!

[chromatographer1]

My guess would be another phase might work better.

Glycerol is too acidic for the column you are using.

Perhaps, a FFAP column might work better, or an ordinary Wax column.

best wishes,

Rodney George
consultant

[TimGG]

Thanks Rodney, I know I should pick a Wax column but just hoping it works~~~ but really appreciated

[Consumer Products Guy]

The "624" columns (e.g. Rtx-624) detailed in the USP monograph (for impurities in glycerin) give a decent peak shape for underivatized glycerin.

At my work we've assayed for glycerin levels in consumer products and raw materials for decades by GC on non-polar capillaries after trimethylsilyl derivatization.

[AICMM]

Sorry, for newbies like me, could someone explain what a CAM column is? Just curious.

Best regards.

[chromatographer1]

A CAM column is a carbowax phase column with the surface/phase deactivated to amines. It has a more basic character than a ordinary Carbowax (PEG) phase like the FFAP phase has a more acidic character than the Carbowax phase, although it too is based on Carbowax.

Rodney George
consultant