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how do you get naquadria

Discussions about HPLC, CE, TLC, SFC, and other "liquid phase" separation techniques.

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I’m not convinced that this is a valid evidence of resolving power in practice, but I can see what they’ve done and maybe it’s OK as a theoretical assumption.
They have calculated the peak capacity in the first purification step (HIC) = 50.
Then they’ve calculated the peak capacity in the second purification step (SEC) = 10.
Then they’ve multiplied these two numbers which results in 500 which they further multiply by peak capacity with the (IEx) step and so on.
I’ve never heard of that kind of resolution estimation, but it might be an OK approach to a theoretical expectation.

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Dancho Dikov

You can multiply these numbers only if the modes of chromatography are orthogonal one to another!
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