Chromatography Forum

Posted: **Fri Sep 20, 2019 4:51 pm**

Task:
Switch to N2 carrier gas

Current practices:
He carrier gas, backpressure-regulated GC's (Agilent). A decent amount of work is injecting neat solvents for purity, use 400:1 split ratio to prevent overload. He is limited by EPC to a total flow of 1250mL/min.

Challenge:
N2 is limited by EPC to a total flow of 200mL/min. The 400:1 split ratio isn't possible.

Any suggestions?

Posted: **Fri Sep 20, 2019 4:56 pm**

Dilute the sample.

Posted: **Mon Sep 23, 2019 12:03 pm**

Are your impurities overloading the column? If not, you could try a splitless injection to get rid of the solvent tail.

Gasman

Posted: **Mon Sep 23, 2019 2:55 pm**

What detector are you using?

What are the dimensions of the column you are using?

Different options can be found depending on more information.

Posted: **Tue Sep 24, 2019 11:22 pm**

Phosgina,

what is keeping you from using H2 instead of N2?

Best regards,

AICMM

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