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Quantitation through LC-MS/MS

Posted: Sun Dec 14, 2008 3:47 pm
by subhrakanti
Hi
For trace label analyte quantitation and confirmation by LCMSMS in a complex matrix quantitation and confirmation ion peak area ratio of targeted analyte is considered. how much deviation of this ratio is acceptable for an analyte from standard sample to matrix sample?

can you suggest me any literature reference for this?