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study of liposomes' size

http://www.chromforum.org/viewtopic.php?t=9556

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study of liposomes' size

Posted: Mon Nov 17, 2008 4:04 pm
by imensaad
I'm interested of finding any methode of on the web, or if any one has, to study the size of liposomes by HPLC.
Thanks

Posted: Wed Nov 19, 2008 7:10 pm
by Slammy1
As opposed to light scattering or microscopy? Liposomes are fairly easily disrupted, and under conditions of pressure and varying solvent strength I cannot imagine you would obtain meaningful data wrt real world characteristics. Perhaps an electrophoretic technique would be more appropriate for the problem? I've heard of people using GPC, you might look into that.
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