durability comparison between different HILIC columns

[jiangds06]

which column is the most durable column? amide, amino, diol or cyano?

[Vlad Orlovsky]

good bare silica is the most stable. Amino and cyano are less stable than any other (IN MOST OF THE CASES). It also depends on operational range of the column and your method.

[jiangds06]

so amino and cyano columns are the least stable column?

good bare silica is the most stable. Amino and cyano are less stable than any other (IN MOST OF THE CASES). It also depends on operational range of the column and your method.