Chromatography Forum

Hi people! can anyone tell me if there exists on the net some table values´s page in order to find quickly the pka of any substance? i´m talking about common pharmaceutical drugs, vitamins, etc...
Thanks!!!!!

I personally use "CRC Handbook of Chemistry and Physics" and "Lange's Handbook of Chemstry" togehther with a few others but if you like online, here is a pdf document:

http://research.chem.psu.edu/brpgroup/p ... lation.pdf

and then there is that one:

http://www.chemicalforums.com/index.php?page=pkavalues

You might find more if you search for them.

thank you so much robert. I appreciate your help!

Another link worth mentioning:

http://www.chem.wisc.edu/areas/reich/pkatable/

thank you so much!!!!, an excellent link!!!

Hello all,
it may be a little too late but her are two other links:
- first drugbank were most of the commercial drugs are cited with phys-chem properties : http://www.drugbank.ca/
-second, an online software that calculate pKa from chemical structure, i found good correlation with litterature values : http://www.vcclab.org/lab/alogps/

Hope it is helpful

cheers