Chromatography Forum

I’m a student and I’m just starting to use gas chromatography. I have some questions and I would appreciate your help.
I'm working with Catalytic Peroxide Wet Oxidation and my samples have acetic acid and H2O2.
I want to measure the concentration of acetic without the interference of the H2O2, or measure both, separating the peaks.
I’m using gas chromatography, a ECONO-CAP capillary column, carbowax 19653 (polyethylene glycol), and the detector is a FID.
I want to now if the H2O2 can damage the column and if it’s possible to measure it with this method, this type of column and detector.

I would say yes it would damage your column and you would be better off looking at an LC method. Ion chromatography ??

I doubt you can measure hydrogen peroxide as a peak, but you should be able to measure acetic acid, depending upon the pH of the solution and how concentrated the aqueous solution is.

Yes it will damage the column but sometimes results cost money.

How much will it cost you to do it by another method? What is your time worth?

Use a short column 5-10 meters and see if you can make it work, unless you have a cheaper way readily available.

You decide.

If you are using an ECONOMY capillary you might have money issues, yes? No?

You should try on RP-HPLC with derivatizing agent sodium borohydrode and benzaldehyde. Which can derivatized H2O2 and you can try ACN and water with RP-18 HPLC column. If you want to more detatils about peroxide u can call me on my persional e-mail ID

Praveen