TLC: plate destruction

Off-topic conversations and chit-chat.

3 posts Page 1 of 1
Hello.
We've tried recently Acetonitrile/Water/Ammonia 4:6:0.2 as a mobile phase with Silicagel & C18 plates both alumina by Merck. After development stationary phase unglued from alumina and alumina got black color.
Any tips please?
Best regards,
Dmitriy A. Perlow
Aluminum is corroded at alkaline pH. Best suggestion would be to switch to glass plates (or avoid alkaline mobile phases).
-- Tom Jupille
LC Resources / Separation Science Associates
tjupille@lcresources.com
+ 1 (925) 297-5374
Both SiO2 & Al can be damaged by hight pH but methanol/ammonia is almost fine mobile phase.
Best regards,
Dmitriy A. Perlow
3 posts Page 1 of 1

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