Chromatography Forum

Posted: **Mon Oct 11, 2004 1:54 pm**

can any body will explain me in detail about LOQ and LOD.
i abruptly know it but i am not able to get its application

Posted: **Mon Oct 11, 2004 2:12 pm**

Try to do some reading, for instance FDA Guidance for Industry, Bioanalytical Method Validation, U.S. Department of Health and Human Services, Food and Drug Administration, Center for Drug Evaluation and Research (CDER), Center for Veterinary Medicine (CVM), May 2001. You can find this document on the FDA website:

www.fda.gov/cder/guidance/4252fnl.pdf

Good luck

Posted: **Thu Oct 14, 2004 2:52 pm**

Check this too you may find this useful.

http://www.fda.gov/cder/guidance/1320fnl.pdf

regards

diya

Posted: **Sat Oct 23, 2004 1:29 pm**

Can LOQ and LOD values lie outside the range as determined from the standard curve?