method development

[kishore1984]

hi

how to develop a bioanalytical/analytical method for a compound
what are the steps to be followed
basics where i can get through

[tom jupille]

The best is probably the book Practical HPLC Method Development by Snyder, Glajch, & Kirkland.

[kishore1984]

sir is it sufficient to lc/ms also sir

[Consumer Products Guy]

Find out the structure, solubility of the material in different solvents, all you can learn. The properties of the material (e.g. volatility, heat stability, whether UV-absorbing, etc.) usually leads to choice of technique.