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method development

Posted: Sun Jun 15, 2008 4:20 pm
by kishore1984
hi

how to develop a bioanalytical/analytical method for a compound
what are the steps to be followed
basics where i can get through

Posted: Mon Jun 16, 2008 4:33 pm
by tom jupille
The best is probably the book Practical HPLC Method Development by Snyder, Glajch, & Kirkland.

thank you sir

Posted: Fri Jun 20, 2008 11:11 am
by kishore1984
sir is it sufficient to lc/ms also sir

Posted: Wed Jul 09, 2008 3:12 pm
by Consumer Products Guy
Find out the structure, solubility of the material in different solvents, all you can learn. The properties of the material (e.g. volatility, heat stability, whether UV-absorbing, etc.) usually leads to choice of technique.