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Levocetrizine Analysis by HPLC

Posted: Sat Jun 14, 2008 9:36 am
by Sharif
hi,

how r u all. anyone know how i can anlyze Lezocetrizine by HPLC.

Posted: Sat Jun 14, 2008 7:02 pm
by Bruce Hamilton
No idea.

However, if you meant Levocetirizine, there are published methods available. It's amazing what a simple Google search for "levocetirizine HPLC" reveals.... eg

If you wish to analyse the bulk product...

Stability indicating HPLC method for the determination of levocetirizine dihydrochloride as bulk and in pharmaceutical dosage forms

Dhaneshwar, S. R. Bhutale, N. K. Mhaske, D. V. Kadam, S. S.
JOURNAL OF PHARMACY AND PHARMACOLOGY. 2006, VOL 58; NUMB 10; SUPP/1, pages 99 ISBN ISSN 0022-3573

Or, if you are monitoring it, the following apparently uses chiral HPLC.

Levocetirizine: Pharmacokinetics and pharmacodynamics in children age 6 to 11 years .
F . Simons , K . Simons
Journal of Allergy and Clinical Immunology , Volume 116 , Issue 2 , Pages 355 - 361

Bruce Hamilton