Anyone have any tips on optimizing ECD equilibration?
Posted: Thu May 29, 2008 7:14 pm
Does anyone have any tips on how best to equilibrate an electrochemical detector? (In general?)
Advice from an experienced chromatographer: zap the dual channel analytical cell with +700mV on both E1 and E2 channels for one minute - then place the electrodes on their prescribed settings and await equilibration. He said it would decrease equilibration time and enhance sensitivity.
I just tried this today and can say that this actually worked and it decreased the very-long time it usually takes to equilibrate (I am using an old ECD).
Anyone else have any other tricks to share?