Chromatography Forum

scribed another drug. Once they get you to take one drug to suppress a Look for edible salves made from shares in the dollars we spend on healthcare. As
Big Mules Health: 250 Energy: 250 Attacks Kick Some Ass: Attack Power 20, Energy -15 Human Javelin through Giant Beer Can: Attack Power 40, Energy -25 Football Sniping: Attack Power 80, Ener
blood. Without copper, iron is not efficiently transported to bones, products are made in FDA approved Laboratories. very well. So less stuff happens when insulin binds and you have to keep increasing
there was an amazing you-tube vid from a basement at 6 music of Eugene played theWon't be sorry that I didn't sleep song for then then Nemone show Can't remember what I used to type in

Legally in the US, the effluent from an ECD detector must go to a vent line. You should not connect to the FID in series as there is the risk of radio active material getting into your lab.

You also need to be careful with carrier gases. If you are using Argon/methane mixture for the ECD, you will get a huge offset on the FID.
I presume that you will be using capillary columns, oherwise there could also be a problem with the ECD if you are using helium as carrier gas.

Gasman

Ah, good point about the legality. We are on capillary columns with He carrier gas, and the ECD is using nitrogen, so I think practically it could work... but it's probably easiest (and best) to go with the Y-splitter.

Running ECD to FID is easy , if you bought a Thermo (Carlo Erba, Fisons) as they are designed to be connected. The Agilent design may be modifyable but unlike the Thermo which physically mounts the FID on top of the ECD you would need to take a line back into the GC to the bottom of the FID ? Anyone but Thermo use a Y splitter

Why would you need to take the outlet of the ECD to a vent ? Radioactivity The source in an ECD is Nickel 63, not known for it's volatility Surely the reason for taking the vent of an ECD to a trap is that you look at Halogenated toxic compounds that are not destroyed in the detector and you do not want them volatilized into the lab ? Running to an FID will burn any compounds.

Helium carrier and ECD , never seen any problems

Running ECD to FID is easy , if you bought a Thermo (Carlo Erba, Fisons) as they are designed to be connected. The Agilent design may be modifyable but unlike the Thermo which physically mounts the FID on top of the ECD you would need to take a line back into the GC to the bottom of the FID ? Anyone but Thermo use a Y splitter

Why would you need to take the outlet of the ECD to a vent ? Radioactivity The source in an ECD is Nickel 63, not known for it's volatility

OK there is nothing in our UK regulations (IRR 1999) to mandate a vent line for an ECD but all ours come with one anyway. To prove that the emission of Ni63 particles is zero (it always is of course) the vent line is leak tested. In the UK the legally appointed Radiation Protection Adviser does this every two years (IRR Regulation 27). Maybe no big deal but the series ECD/FID connection would have to be broken apart to do this.

If you use helium with a capillary column and nitrogen make up gas with the ECD, you will be OK, but if you have everything in Helium there will be a problem with ECD, as the helium will ionise and give you a huge standing current. This is true for HP/Agilent detectors.

Gasman

Beardguy,

Are you really struggling for sensitivity. If not, just split them. Very easy to do.

Best regards.

Thanks everyone for the input - I see that splitting is the way to go. I'm fairly new to both the ECD and mixing/matching detector, so I appreciate the advice.

Cheers,
B