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Calculating concentration from GC

Posted: Thu Apr 10, 2008 6:00 pm
by forensicgirl
Hi, I need to know how to calculate the concentration of paracetamol from my GC. The standard that was run with it was 3-acetamidophenol. I know the concentration of this, and the peak areas for both.

Posted: Sat Apr 12, 2008 12:18 pm
by Willy
Hello Dear,

If i understand you question you are analysing Acetaminophen(paracetamol) and you are using a different standard to try to quantify 3-acetamidophenol (metacetamol)...seems like they both are position isomers. I dont know the reason why but i would recommend using same standard to analyse it because the response factor could be different even at same molecular mass. But if its only a question of conversion the calculation would be:

Area sample/area std * concentration std/diluting factor of sample*100%
since they have same molecular mass.

Hope it help

Willy the GC :D