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Cytarabine USP Monograph

Posted: Thu Feb 08, 2018 2:41 pm
by apdoyle
Hi,

A question on the cytarabine USP HPLC related substances method, which gives a relative response factor of 1.5 for Impurity 1 (RRT 0.38) and Impurity 2 (RRT 0.43).

Does anybody know the identity of these impurities? I can't find any info online - strange that RRFs are provided for impurities whose identities are all but hidden!

Any references would be greatly appreciated,

Thanks in advance
apd

Re: Cytarabine USP Monograph

Posted: Thu Feb 08, 2018 9:13 pm
by mattmullaney
Good afternoon,

Does this help?

https://www.bocsci.com/im-cytarabine-an ... t-692.html

No IDs, unfortunately.