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isocratic rp lc.. binding?

Posted: Thu Apr 03, 2008 4:37 pm
by alicee!
hii alll.. i m trying to understand the mechanism for isocratic rp-hplc..
here if my molecule enters with a mobile phase concentration where it is eluting.. will it bind? or it is done at an optima.. where there is an equilibrium between binding and elution.. m i missing something? let me know plss.. thanks!

Posted: Fri Apr 04, 2008 12:00 am
by tom jupille
Could you re-phrase the question?