Chromatography Forum

Hi all, first time posting here.
I am an engineer/chemist who is in charge of analytics for an analytical company in CA. We have an old 5890 series 2 w/ an FID sitting in a facility here, and I was wondering if there is a possibility to use it for pesticide detection in oils of botanical extracts?
I am not too familiar with the limitations of this machine.
We are planning to use it for cannabis testing purposes. Thc and CBD, along with residual solvent analysis. I do not know if it can analyze and detect the pesticides we are currently working with in these samples.

Myclobutanil, Bifenezate, Imidacloprid, and Spiromesifen are just some of the pesticides I encounter, and need to make sure are not in the test samples.

Usually a LC-MS is used to check for these pesticides, but we don't have one on site currently. I was wondering if I would even be able to detect these pesticides in the samples using this HPGC or not...?

Thanks in advance!

It is possible to detect them, but the amount you can detect with FID is very different than LCMS. For pesticides you would probably be in mid ppm detection ranges with FID while on LCMS you will be in the low ppb ranges normally, maybe even lower with LCMSMS.

You will not get bifenazate and myclobutanil through a GC inlet. Don't know about spiromesifin but from the structure it is doubtful. The FID will respond to the oils, so you will end up with a lot of peaks and no way to definitively determine the pesticides in amongst the interferences.

If you can't afford a LC-MS/MS then you probably need to send the sample out for analysis.

Thanks guys!

Im going to be sending the samples out for analysis, until our LC-MS/MS gets installed.