Chromatography Forum

Hey, guys & gals!

I get Agilent GC and Chemstation workstation (B.02.01 & B.03.01) in my lab. When I use them to validate GC method, a problem arises when the validation process comes to Quatitation Limit and Detection Limit determination. The workstation gives three noise calculation values (6*SD, PtoP, ASTM), and they differs. I am comfused by them. I want to know which one you choose to calculate Signal/Noise ratio.

Many thanks in advance.

Terry,

Perhaps this previous discussion will help clarify things:

http://www.sepsci.com/chromforum/viewtopic.php?t=7146

Also, there have been several other dicsussions in the forum on the topic of S/N. Please use the search feature for additional info.

Regards,
Dan

Thank you, Dan.

It helps